89032-81-5

Basic information

• Product Name: 1,2,4-Oxadiazole-3-carboxylic acid, methyl ester (6CI,7CI)
• Synonyms: 1,2,4-Oxadiazole-3-carboxylic acid, methyl ester (6CI,7CI);methyl 1,2,4-oxadiazole-3-carboxylate;MFCD22628348
• CAS NO: 89032-81-5
• Molecular Formula: C4H4N2O3
• Molecular Weight: 128.08616
• Product Categories: ACIDHALIDE
• Mol File: 89032-81-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 191.4±23.0 °C(Predicted)
• Appearance: /
• Density: 1.326±0.06 g/cm3(Predicted)
• PKA: -4.85±0.10(Predicted)
• CAS DataBase Reference: 1,2,4-Oxadiazole-3-carboxylic acid, methyl ester (6CI,7CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Oxadiazole-3-carboxylic acid, methyl ester (6CI,7CI)(89032-81-5)
• EPA Substance Registry System: 1,2,4-Oxadiazole-3-carboxylic acid, methyl ester (6CI,7CI)(89032-81-5)

Safety Data

• Hazardous Substances Data: 89032-81-5(Hazardous Substances Data)

Usage

Structure

Methyl ester derivative of 1,2,4-oxadiazole-3-carboxylic acid

Functional groups

Five-membered oxadiazole ring, carboxylic acid group, and methyl ester group

Upstream product

• 1217428-98-2 ethyl 2-oximinooxamate 
• 122-51-0 orthoformic acid triethyl ester 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 1154990-12-1 (1,2,4-oxadiazol-3-yl)methanol 

Relevant articles and documents

COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES

The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound useful in the treatment of a neurodegenerative disorder and their combined use as a medicament, in particular for the treatment of neurodegenerative and/or cognitive disorders.

1H-PYRAZOLO[4,3-B]PYRIDINES AS PDE1 INHIBITORS

The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.