89046-68-4Relevant academic research and scientific papers
Acyclic Stereocontrol Based on Chelation-Controlled Ene Reaction with Chiral α- and β-Alkoxyaldehydes
Mikami. Koichi,Loh, Teck-Peng,Nakai, Takeshi
, p. 13 - 16 (1990)
The Lewis acid-promoted ene reactions with chiral α- and β-benzyloxyaldehydes have been developed and shown to afford high levels of both diastereofacial (chelation) selection and simple diastereoselection (anti), thus providing an efficient method for stereocontrol over three contiguous chiral centers.
