89051-52-5Relevant academic research and scientific papers
THE TRAPPING OF SULFENIC ACIDS FROM PENICILLIN SULFOXIDES. HETEROCYCLIC MERCAPTANS
Micetich, Ronald G.,Maiti, Samarendra N.,Tanaka, Motoaki,Yamazaki, Tomio,Ogawa, Kazuo
, p. 325 - 330 (2007/10/02)
Various heterocyclic thiols have been used for trapping the azetidinone sulfenic acids obtained by the thermolysis of penicillin sulfoxides.The ester function was found to be important in determining the unsym-azetidinone disulfide (α,β- or β,γ-unsaturated) isomer formed.All β,γ-isomers prepared reacted with cupric chloride to give the 2-chloromethylpenams.
