89059-53-0Relevant academic research and scientific papers
A STUDY OF THE MICHAEL REACTION OF 2'-HYDROXYCHALCONES AND A FACILE FORMATION OF 4H-PYRAN DERIVATIVES
Jain, Amolak Hand,Arya, Prabhat,Sharma, Anita
, p. 2369 - 2378 (2007/10/02)
2'-Hydroxychalcones (8a) and (8b) when subjected to the Michael reaction with acetyl acetone in the presence of ethanolic piperidine gave the 4H-pyran derivatives (9a) and (9b) besides the cyclohexenone derivatives (10a and 11a) and (10b and 11b) respectively.However, 8c yielded under the same conditions only the 4H-pyran derivative (9c) together with some 5,7-dimethoxyflavanone (12c).Thus 4H-pyrans have, for the first time, been characterized during Michael condensation of chalcones having no electron withdrawing group in the α-position.Ethyl acetoacetate gives only cyclohexenone derivatives.
