890655-08-0Relevant articles and documents
NOVEL PROCESSES FOR THE PREPARATION OF 2-OXY-BENZOXAZINONE DERIVATIVES
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Page/Page column 17, (2018/02/28)
Provided herein are novel, commercially viable and industrially advantageous processes for the preparation of 2-hexadecyloxy-6-methyl-4H-3,1-benzoxazin-4-one, and its intermediates, in high yield and purity.
A he west for favorable department method of preparation
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, (2017/01/31)
The invention discloses a method for preparing cetilistat, which belongs to the technical field of the medicine preparation method, and is used for solving the problems of high three wastes, low yield and high cost in the current preparation method. The method comprises the following steps: 1)esterifying a compound A(2-amino-5-methyl benzoic acid) or its salt; 2) acylating an esterification object in the step 1) and chloroformic acid n-cetanol ester; 3)removing ester group of the compound obtained in the step 2) to obtain 2-(cetane carbonyl oxygen)amino-5-methyl benzoic acid; and 4)cyclizing the compound in the step 3) to obtain the target products. By improving the production steps, the invention provides the synthetic method with simple operation, high efficiency, and convenient industrial production for the cetilistat product.
One-pot high-yielding preparation of cetilistat
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Paragraph 0027; 0028; 0029, (2016/11/21)
The invention relates to a new process for one-pot preparation of cetilistat; the one-pot reaction is adopted, separation steps are sample, the product yield is high, the product quality is good, and the new process is especially suitable for industrialized production.