890657-32-6Relevant academic research and scientific papers
A new modular indole synthesis. Construction of the highly strained CDEF parent tetracycle of nodulisporic acids A and B
Smith III, Amos B.,Kuerti, Laszlo,Davulcu, Akin H.
, p. 2167 - 2170 (2007/10/03)
Construction of the highly strained CDEF parent tetracycle, a structural motif found only in the potent ectoparasiticidal agents (+)-nodulisporic acids A and B and related congeners, has been achieved via a new modular indole synthesis, exploiting a sequential Stille cross-coupling/Buchwald-Hartwig union/cyclization tactic. The new indole synthesis holds the promise of rapid assembly of diverse, highly substituted indoles possessing uncommon substitution patterns.
