89066-10-4Relevant academic research and scientific papers
Catalytic enantioselective oxidation of bulky alkyl aryl thioethers with H2O2 over titanium-salan catalysts
Bryliakov, Konstantin P.,Talsi, Evgenii P.
, p. 4693 - 4698 (2011/10/03)
A simple and efficient catalytic procedure for the oxidation of bulky (preferably aryl benzyl substituted) thioethers with hydrogen peroxide in good to high yields and enantioselectivities (up to 98.5%ee) is reported. The high optical yields are achieved in a tandem stereoconvergent enantioselective oxidation and kinetic resolution process. A reasonable balance between the sulfoxide yield and enantioselectivity could be found by varying the concentration and temperature. An improved synthesis of the titanium-salan catalysts for the preparation of a more stereoselective catalyst is reported.
WO3-30% H2O2-cinchona alkaloids: A new heterogeneous catalytic system for the asymmetric oxidation of sulfides and the kinetic resolution of racemic sulfoxides
Thakur, Vinay V.,Sudalai
, p. 407 - 410 (2007/10/03)
WO3-catalyzed asymmetric oxidation of thioethers and kinetic resolution of sulfoxides with 30% aq. H2O2 in the presence of cinchona alkaloids under heterogeneous conditions affords chiral sulfoxides in high yields with moderate to good enantioselectivities.
