89067-59-4Relevant articles and documents
ETUDES DE LIGNANES 7 - SYNTHESES TOTALES DES (+-)-α ET -β-CONIDENDRINES ET DES METHYL (+-)-α ET -β-CONIDENDRALS
Dhal, Robert,Nabi, Yahia,Brown, Eric
, p. 2005 - 2016 (2007/10/02)
Michael addition of the carbanion of the dithian 8 on butenolide, followed by alkylation with the benzylic bromide 11 and regeneration of the ketonic carbonyl group, gave the α,β-disubstituted lactone 13.Reduction of the ketonic carbonyl of the latter usi
SYNTHESE TOTALE DE LA (d,l) α-CONIDENDRINE
Nabi, Yahia,Dhal, Robert,Brown, Eric
, p. 1543 - 1546 (2007/10/02)
Michael addition of the carbanion of the dithian 7 (derived from O-benzylvanillin) on butenolide, afforded the saturated lactone 8.Alkylation of the latter with the benzylic bromide 6, followed by regeneration of the carbonyl group gave the α,β-disubstituted lactone 10.Reduction of the ketonic carbonyl group of compound 10 using NaBH4, followed by treatment with CF3CO2H and catalytic hydrogenolysis afforded (d,l)α-conidendrin 1.