890709-66-7

Basic information

• Product Name: (S)-2-Methyl-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester
• Synonyms: (S)-2-Methyl-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester;(S)-tert-Butyl 2-Methyl-3,5-dioxopyrrolidine-1-carboxylate
• CAS NO: 890709-66-7
• Molecular Formula: C₁₀H₁₅NO₄
• Molecular Weight: 213.2304
• Mol File: 890709-66-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-2-Methyl-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Methyl-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester(890709-66-7)
• EPA Substance Registry System: (S)-2-Methyl-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester(890709-66-7)

Safety Data

• Hazardous Substances Data: 890709-66-7(Hazardous Substances Data)

Usage

General Description

(S)-2-Methyl-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester is a compound with the chemical formula C11H17NO4. It is a tert-butyl ester derivative of a pyrrolidine carboxylic acid, which is a key intermediate in the synthesis of various pharmaceuticals and organic compounds. This chemical is used as a building block in the production of drugs, agrochemicals, and other fine chemicals. It has potential applications in the pharmaceutical industry as a chiral building block, and its stereochemistry is important for its biological activity. (S)-2-Methyl-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester is typically handled and stored under controlled conditions due to its reactivity and potential hazards.

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 15761-38-3 L-N-Boc-Ala 
• 24424-99-5 di-tert-butyl dicarbonate 
• 223678-95-3 tert-butyl N-[(1S)-2-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)-2-hydroxy-1-methylethyl]carbamate 
• 3744-87-4 N-t-butyloxycarbonyl-DL-alanine 

Downstream Products

• 1388684-75-0 C₁₇H₂₁NO₆S 
• 1316848-21-1 (S)-5-benzyl-4-(tert-butoxy)-1-((S)-1-((S)-2-methyl-5-oxo-2,5-dihydro-1H-pyrrol-3-yl)pyrrolidin-3-yl)-1H-pyrrol-2(5H)-one 
• 890709-77-0 [(S)-1-Benzyl-2-((S)-3-ethoxy-2-methyl-5-oxo-2,5-dihydro-pyrrol-1-yl)-2-oxo-ethyl]-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 151004-17-0 (5S)-5-methyl-2,4-dioxopyrrolidine 

Relevant articles and documents

6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES

The present invention relates to compounds of the formula (I) or pharmaceutically acceptable salts, enantiomer or diastereomer thereof, wherein R1 to R4 are as described above. The compounds may be useful for the treatment or prophylaxis of hepatitis B virus infection.

A synthetic approach to diverse 3-acyltetramic acids via O- to C-acyl rearrangement and application to the total synthesis of penicillenol series

For the efficient approach to medicinally important α-branched 3-acyltetramic acids, the key reaction of O- to C- acyl rearrangement using α-amino-acid-derived 4-O-acyltetramic acids was extensively examined in the presence of various metal salts. Use of

Synthesis of the peptide moiety of the jamaicamides

The jamaicamides, isolated from cyanobacterium Lyngbya majuscula in Jamaica, are unique mixed polyketide-peptides that are reported to be blockers of the sodium channels. The peptide moiety contains a pyrrolinone ring and a β-methoxy enone functionality. Herein, we report the stereoselective synthesis of the N-(Boc)2-protected peptide moiety of the jamaicamides by utilizing Meldrum's acid starting from l-alanine and N-Boc-β-alanine.