890715-18-1 Usage
Description
4-(Furan-3-yl)benzoic acid is a chemical compound with the molecular formula C11H8O3, characterized by a benzoic acid structure with a furan ring attached at the 4-position. This derivative is known for its potential in various chemical and pharmaceutical applications due to its unique structural features.
Uses
Used in Pharmaceutical Industry:
4-(Furan-3-yl)benzoic acid is used as a building block for the synthesis of various drugs and biologically active molecules, leveraging its structural properties to contribute to the development of new therapeutic agents.
Used in Organic Chemistry:
In the field of organic chemistry, 4-(Furan-3-yl)benzoic acid is used for the synthesis of heterocyclic compounds, taking advantage of the furan ring's reactivity and the compound's potential to form diverse chemical structures.
Used in Dye and Pigment Production:
4-(Furan-3-yl)benzoic acid is utilized in the production of dyes and pigments, where its chemical properties contribute to the creation of a range of colorants for various applications.
Used in Material Science:
4-(Furan-3-yl)benzoic acid is also employed in the development of new materials, where its structural features and chemical properties can enhance material properties or enable the creation of novel materials with specific characteristics.
Used in Medicinal Chemistry and Drug Discovery:
Due to its structural features and pharmacological properties, 4-(Furan-3-yl)benzoic acid has potential applications in medicinal chemistry and drug discovery, where it may serve as a key component in the design and synthesis of new pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 890715-18-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,0,7,1 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 890715-18:
(8*8)+(7*9)+(6*0)+(5*7)+(4*1)+(3*5)+(2*1)+(1*8)=191
191 % 10 = 1
So 890715-18-1 is a valid CAS Registry Number.
890715-18-1Relevant articles and documents
Design, synthesis, and biological activity evaluation of 2-(benzo[b]thiophen-2-yl)-4-phenyl-4,5-dihydrooxazole derivatives as broad-spectrum antifungal agents
Zhao, Liyu,Sun, Yin,Yin, Wenbo,Tian, Linfeng,Sun, Nannan,Zheng, Yang,Zhang, Chu,Zhao, Shizhen,Su, Xin,Zhao, Dongmei,Cheng, Maosheng
, (2021/11/22)
To discover antifungal compounds with broad-spectrum and stable metabolism, a series of 2-(benzo[b]thiophen-2-yl)-4-phenyl-4,5-dihydrooxazole derivatives was designed and synthesized. Compounds A30-A34 exhibited excellent broad-spectrum antifungal activity against Candida albicans with MIC values in the range of 0.03–0.5 μg/mL, and against Cryptococcus neoformans and Aspergillus fumigatus with MIC values in the range of 0.25–2 μg/mL. In addition, compounds A31 and A33 showed high metabolic stability in human liver microsomes in vitro, with the half-life of 80.5 min and 69.4 min, respectively. Moreover, compounds A31 and A33 showed weak or almost no inhibitory effect on the CYP3A4 and CYP2D6. The pharmacokinetic evaluation in SD rats showed that compound A31 had suitable pharmacokinetic properties and was worthy of further study.
