89075-52-5 Usage
Structure
Heterocyclic aromatic compound
It contains both imidazole and pyridine rings, which are fused together to form a heterocyclic structure.
Substituent
2-(4-methylphenyl)-
A methylphenyl group is attached to the 2 position of the imidazo[4,5-c]pyridine core, providing additional structural complexity.
Functional groups
Imidazole and pyridine rings
These two heterocyclic rings are the primary functional groups in the molecule, contributing to its unique properties.
Applications
Pharmaceutical synthesis
The compound is used in the synthesis of various pharmaceuticals and organic compounds due to its unique structure and properties.
Potential
Biological activities and drug discovery
It may have potential biological activities and applications in drug discovery and development, making it a valuable compound for research.
Solubility
Unknown
The solubility of the compound is not provided in the material, but it may be influenced by the presence of the aromatic rings and the substituent.
Stability
Unknown
The stability of the compound is not provided in the material, but it is likely to be influenced by the aromaticity of the imidazole and pyridine rings.
Reactivity
Unknown
The reactivity of the compound is not provided in the material, but it may be influenced by the presence of the nitrogen atoms in the imidazole and pyridine rings.
Physical state
Unknown
The physical state (solid, liquid, or gas) of the compound is not provided in the material, but it is likely to be a solid at room temperature due to its molecular size and complexity.
Check Digit Verification of cas no
The CAS Registry Mumber 89075-52-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,0,7 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 89075-52:
(7*8)+(6*9)+(5*0)+(4*7)+(3*5)+(2*5)+(1*2)=165
165 % 10 = 5
So 89075-52-5 is a valid CAS Registry Number.
89075-52-5Relevant academic research and scientific papers
Na2S2O4: A versatile reagent for the one-pot synthesis of 2-aryl-1h-imidazo[4,5-c]pyridines from 4-amino-3- nitropyridine and aldehydes via reductive cyclization
Dubey,Chowdary,Ramesh,Reddy, P. V. V. Prasada
, p. 697 - 708 (2011/03/19)
A highly efficient and versatile method for the synthesis of 2-aryl-1H-imidazo[4,5-c]pyridines 3 was achieved in one step via reductive cyclization of 4-amino-3-nitro-pyridines 4 with aromatic aldehydes in the presence of Na2S2O
Structure-activity relationships of arylimidazopyridine cardiotonics: Discovery and inotropic activity of 2-[2-methoxy-4-(methylsulfinyl)phenyl]-1H-imidazo[4,5-c]pyridine
Robertson,Beedle,Krushinski,Pollock,Wilson,Wyss,Hayes
, p. 717 - 727 (2007/10/02)
Recently several noncatecholamine, nonglycoside cardiotonic drugs have been discovered that possess both inotropic and vasodilator activities in experimental animals and man. Prototypical compounds include amrinone, sulmazole, and fenoximone. We investigated the structural requirements necessary for optimal inotropic activity in a series of molecules containing a heterocyclic ring fused to 2-phenylimidazole and discovered that 2-phenylimidazo[4,5-c]pyridines were generally 5-10-fold more potent than analogous 2-phenylimidazo[4,5-b]pyridines (e.g., sulmazole) or 8-phenylpurines. Furthermore, all imidazo[4,5-c]pyridine analogues we tested were orally active; in contrast, only one of the imidazo[4,5-b]pyridine derivatives, sulmazole, was significantly active. One of several highly active compounds in the [4,5-c] series was 50 (LY175326, 2-[2-methoxy-4-(methylsulfinyl)phenyl]-1H- imidazo[4,5-c]pyridine hydrochloride). The structure-activity relationship of this series is presented and compared to that of the imidazo[4,5-b]pyridine and purine series.
