89080-40-0Relevant academic research and scientific papers
A mild and convenient one-pot synthesis of 4-aryl-n-oh-hantzsch esters
Miao, Chun-Bao,Dong, Chun-Ping,Wang, Yan-Hong,Yang, Hai-Tao,Meng, Qi,Tu, Shu-Jiang,Sun, Xiao-Qiang
, p. 853 - 859 (2013/05/08)
A general methodology to prepare a series of 4-Aryl-N-OH Hantzsch esters was developed. The key factor is to control the first-step of Michael addition at 0 °C. The method was practical to produce symmetrical and unsymmetric N-OH-Hantzsch esters in moderate yield. This class of compounds might have use in medicinal and material science.
