890847-37-7

Upstream product

• 99-93-4 4-Hydroxyacetophenone 
• 55368-24-6 1-(4-(2-bromoethoxy)phenyl)ethan-1-one 
• 103-67-3 benzyl-methyl-amine 

Downstream Products

• 852360-15-7 6-{4-[2-(benzyl-methyl-amino)-ethoxy]-phenyl}-4-methylsulfanyl-2-oxo-2H-pyran-3-carbonitrile 
• 890847-38-8 1-{4-[2-(benzyl-methyl-amino)-ethoxy]-phenyl}-2-bromo-ethanone 

Relevant academic research and scientific papers

NOVEL INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE

Disclosed herein are carbonyl compounds of Formula: (I) as described herein. Compounds as modulators of histone deacetylase (HDAC), pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.

6-Aryl-4-methylsulfanyl-2H-pyran-2-one-3-carbonitriles as PPAR-γ activators

Various 6-aryl-3-cyano/methoxycarbonyl-4-methylsulfanyl-2H-pyran-2-ones have been synthesized as a potential substitute of 2,4-thiazolidinedione head group to express potent PPAR-γ transactivation response. Some of the screened compounds have shown promis