89090-29-9

Upstream product

• 89090-28-8 2,4-dichloro-3-(2-methylphenyl)quinoline 
• 89080-82-0 2,4-Dimethoxy-3-o-tolyl-quinoline 

Downstream Products

• 110509-41-6 [2-(4-Methoxy-3-o-tolyl-quinolin-2-ylsulfanyl)-ethyl]-dimethyl-amine 
• 89080-83-1 4-methoxy-3-o-tolylquinolin-2-thione 

Relevant academic research and scientific papers

Synthesis and 5-Hydroxytryptamine Antagonist Activity of 2-thio>-3-phenylquinoline and Its Analogues

A series of 2-quinolines substituted at the 3-position with alkyl, aryl, or heteroaryl groups has been prepared in the search for novel and selective 5-HT2 antagonists.The affinity of the compounds for 5-HT1 recep

Quinoline derivatives which are 5-hydroxytryptamine antagonists

Compounds of the formula: STR1 wherein A stands for the radical --(CH2)2 -- which may optionally be substituted by one or two (1-2C)alkyl radicals; Q stands for an oxygen or sulphur atom; R° stands for a (1-4C)alkyl, (1-4C)alkoxy or cyclopropyl radical; R1 stands for a defined (3-4C)alkyl radical, a phenyl radical which may optionally bear a defined substituent, or a defined heteroaryl radical of 5 or 6 ring atoms; and R2 and R3 stand for hydrogen or a (1-2C)alkyl radical; and pharmaceutically-acceptable acid-addition salts thereof. Processes for the manufacture of said compounds. Pharmaceutical compositions comprising one of said compounds and a pharmaceutical diluent or carrier. The compounds are 5-hydroxytryptamine antagonists.