89109-19-3

Upstream product

• 51171-02-9 3-bromo-pyrazine-2-carboxylic acid methyl ester 

Downstream Products

• 89108-61-2 7-(n-Butyl)-8-hydroxy-5-phenylpyrido-[2,3-b]pyrazine-6(5H)-one 
• 115891-65-1 8-hydroxy-7-(3-methyl-2-butenyl)-5-phenylpyrido<2,3-b>pyrazin-6(5H)-one 

Relevant academic research and scientific papers

Pyrazine-2-carboxyamide derivatives

The present invention is concerned with novel pyrazine 2-carboxyamide derivatives of formula (I) wherein R1, R2 and R3 are as defined in the specification. These compounds are useful for the treatment of CNS disorders.

Method of treating hyperproliferative skin disease

A method of treating hyperproliferative skin disease with substituted quinoline, [1,5]- and [1,8]- naphthyridine and pyrido[2,3-b]pyrazine derivatives is disclosed. The compounds are also anti-allergic, anti-inflammatory and cytoprotective agents. Methods

Tricyclic positive inotropic agents

Substituted quinoline, [1,5]- and [1,8]-naphthyridine and pyrido [2,3-b]pyrazine derivatives are useful positive inotropic agents.

Tricyclic anti-allergy and use as anti-inflammatory agents

Substituted quinoline, [1,5]- and [1,8]-naphthyridine and pyrido[2,3-b]pyrazine derivatives are anti-allergic, anti-inflammatory and cytoprotective agents. Methods for their preparation and use are disclosed.

Substituted hetero spiro pyridine derivatives as anti-allergy and anti-inflammatory agents

Substituted heterospiro pyridine derivatives are anti-allergic and anti-inflammatory agents. They are also useful for the treatment of peptic ulcers. Methods for their preparation and use are disclosed.

1-Phenyl-1,8-naphthridin-2(1H)-ones

Certain substituted 1,8-naphthyridines and 1,5,8-azanaphthyridines are useful for treating allergic reactions in mammals. Certain of the compounds may also be utilized to treat chronic obstructive lung diseases in mammals. Methods for preparing the co

Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug

Certain substitute 1,8-naphthyridines and 1,5,8-azanaphthyridines are useful in treating and preventing ulcers in mammals. Methods for preparing the compounds and methods for their use are also described.