89117-97-5

Upstream product

• 89118-04-7 2-(3-{2-[Benzyl-((E)-3-oxo-but-1-enyl)-amino]-ethyl}-1H-indol-2-yl)-acrylic acid methyl ester 
• 94846-81-8 1,2,3,4,5,5a,6,10b-Octahydro-azepino[4,5-b]indole-5-carboxylic acid methyl ester 
• 89118-28-5 methyl 3-(4-but-3-ene-2-one-yl)-1,2,3,4,5,6-hexahydroazepino(4,5-b)indole-5-carboxylate 
• 66859-30-1 methyl 3-benzyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole-5-carboxylate 
• 146681-75-6 2-[3-(2-Benzylamino-ethyl)-1H-indol-2-yl]-3-hydroxy-propionic acid methyl ester 

Downstream Products

• 6792-12-7 19-oxovincadifformine 

Relevant academic research and scientific papers

Syntheses of strychnos- and aspidospermatan-type alkaloids. 5. Total syntheses of (±)-echitamidine and 20-epi- and 19-epi-20-epi-echitamidine

Intramolecular Diels-Alder reactions, at two stages in the reaction sequence, provided total syntheses of the racemate of the hypotensive alkaloid echitamidine (8) and of its C-19,20 and C-20 epimers 9a and 9b.

Synthesis of vinca alkaloids and related compounds, Part LXXXIX. Some unexpected reactions of compounds containing the D-seco-aspidospermane ring system

Interaction of the tryptamine derivative (3) with the formyl ester (4) gave (±)-20-deethyl-2,16-didehydro-14,16-bis(methoxycarbonyl)-3-phenyl-3,14- seco-20-epiaspidospermidine (7) instead of the expected acetal (6). The product of the reaction of 3 with t

Studies in biomimetic alkaloids syntheses - 9. Two total syntheses of minovincine

Condensation of methyl 1,2,3,4,5,6-hexahydroazepino[4,5-b]indole-5-carboxylate with the ethylene ketal of 2-acetyl-5-chloropentanal, followed by reactions with triethylamine and aqueous acid gave minovincine. Alternatively, a condensation of the indoloaze