891202-43-0Relevant academic research and scientific papers
RuHCl(CO)(PPh3)3-catalyzed reductive dimerization of α,β-unsaturated aldehydes leading to α-hydroxymethyl ketones
Doi, Takashi,Fukuyama, Takahide,Minamino, Satoshi,Ryu, Ilhyong
, p. 3013 - 3016 (2006)
The reductive dimerization α,β-unsaturated aldehydes to give saturated ketones was achieved using RuHCl(CO)(PPh3)3 as a catalyst in the presence of secondary alcohols as hydrogen source. The reaction is likely to proceed via the hydroruthenation of α,β-unsaturated aldehydes followed by aldol reaction of the resultant ruthenium enolates with α,β-unsaturated aldehydes to give unsaturated α-hydroxymethyl ketones, which undergo transfer hydrogenation to give α-hydroxymethyl ketones. Georg Thieme Verlag Stuttgart.
An unusual dimerization of primary unsaturated alcohols catalyzed by RuHCl(CO)(PPh3)3
Doi, Takashi,Fukuyama, Takahide,Minamino, Satoshi,Husson, Guillaume,Ryu, Ilhyong
, p. 1875 - 1877 (2008/03/14)
When primary unsaturated alcohols were treated with a catalytic amount of RuHCl(CO)(PPh3)3 in benzene under reflux, dimerization reactions took place to give α-hydroxymethyl ketones as major product. The Royal Society of Chemistry 2006.
