89131-42-0

Basic information

• Product Name: Butanoic acid, 2-amino-4-(hydroxyphosphinyl)-
• CAS NO: 89131-42-0
• Molecular Formula: C4H10NO4P
• Molecular Weight: 167.101
• Mol File: 89131-42-0.mol

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2-amino-4-(hydroxyphosphinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-amino-4-(hydroxyphosphinyl)-(89131-42-0)
• EPA Substance Registry System: Butanoic acid, 2-amino-4-(hydroxyphosphinyl)-(89131-42-0)

Safety Data

• Hazardous Substances Data: 89131-42-0(Hazardous Substances Data)

Upstream product

• 89131-41-9 O-ethyl-vinylphosphonite 
• 1068-90-2 2-acetylaminomalonic acid diethyl ester 
• 89131-53-3 Ethyl 3,3-dicarbethoxy-3-acetamidopropylphosphonous acid 
• 55327-87-2 2-acetamidomalonic acid 

Relevant articles and documents

Convenient syntheses of phosphinic analogues of γ-aminobutyric- and glutamic acids

Three-steps, one-pot synthesis of 2-amino-4-(hydroxyphosphinyl)butyric acid from dibutyl ester of vinylphosphinic acid was carried out with an overall yield of 66%. 3-Aminopropylphosphinic acid was prepared from allylamine in three steps with an overall y

1-Aminoalkylphosphonous Acids. Part 1. Isosteres of the Protein Amino Acids

The synthesis of 1-aminoalkylphosphonous acids, isosteres of the protein amino acids, by addition of hypophosphorous acid to diphenylmethylimines is described.These analogues of glycine, alanine, valine, leucine, isoleucine, phenylalanine, tyrosine, tryptophan, serine, threonine, methionine, cysteine, cystine, glutamic acid, lysine, ornithine, arginine, and proline have been prepared and the analogues of alanine, valine, leucine, phenylalanine, and methionine resolved.The alanine, valine and methionine analogues have interesting antimicrobial activity and the alanine analogue has plant growth inhibiting properties.Oxidation of the appropriate 1-aminoalkylphosphonous acids gave the 1-aminoalkylphosphonic acid analogues of (+/-)-alanine, (-)-alanine, (+/-)-valine, (-)-valine, (+/-)-serine, (+/-)-threonine, (+/-)-lysine, (-)-leucine, and (+/-)-ornithine.

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