891491-89-7

Basic information

• Product Name: (6R,4'S,5'R)-6-(2',2'-dimethyl-5'-phenyl-[1',3']dioxolan-4'-yl)-3-phenylselanyltetrahydropyran-2-one
• Synonyms: (6R,4'S,5'R)-6-(2',2'-dimethyl-5'-phenyl-[1',3']dioxolan-4'-yl)-3-phenylselanyltetrahydropyran-2-one
• CAS NO: 891491-89-7
• Molecular Weight: 431.39
• Mol File: 891491-89-7.mol

Chemical Properties

• CAS DataBase Reference: (6R,4'S,5'R)-6-(2',2'-dimethyl-5'-phenyl-[1',3']dioxolan-4'-yl)-3-phenylselanyltetrahydropyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (6R,4'S,5'R)-6-(2',2'-dimethyl-5'-phenyl-[1',3']dioxolan-4'-yl)-3-phenylselanyltetrahydropyran-2-one(891491-89-7)
• EPA Substance Registry System: (6R,4'S,5'R)-6-(2',2'-dimethyl-5'-phenyl-[1',3']dioxolan-4'-yl)-3-phenylselanyltetrahydropyran-2-one(891491-89-7)

Safety Data

• Hazardous Substances Data: 891491-89-7(Hazardous Substances Data)

Upstream product

• 216769-09-4 (2R,2'R,6'R)-2-hydroxy-2-(6'-tert-butyldiphenylsilanyloxymethylpyranyl)-1-phenylethanone 
• 216769-13-0 (2S,2'R,6'R)-2-hydroxy-2-(6'-tert-butyldiphenylsilanyloxymethylpyranyl)-1-phenylethanone 
• 891491-87-5 Z-(2R,2'R)-trimethyl-[1-phenyl-2-(6'-tert-butyldiphenylsilanyloxymethylpyran-2'-yloxy)-vinyloxy]-silane 
• 216769-17-4 (4R,5S,2'R,6'R)-2,2-dimethyl-5-(6'-tert-butyldiphenylsilanyloxymethylpyran-2'-yl)-4-phenyl-[1,3]dioxolane 
• 891491-88-6 (1R,2R)-1-[(2R,6R)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-tetrahydro-pyran-2-yl]-2-phenyl-ethane-1,2-diol 
• 216769-40-3 (R,R)-N-methoxy-N-methyl-2-(6'-tert-butyldiphenylsilanyloxymethylpyranyloxy)-acetamide 
• 216769-05-0 (R,R)-2-(6'-tert-butyldiphenylsilanyloxymethylpyranyloxy)-1-phenylethanone 
• 216769-01-6 (R)-6-(tert-butyldiphenylsilanyloxymethyl)-tetrahydropyran-2-ol 
• 216769-55-0 (6R,4'S,5'R) 6-(2',2'-dimethyl-5'-phenyl-[1',3']dioxolan-4'-yl)-pyranyl acetate 
• 216769-22-1 (2R,6R)-6-((4S,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-tetrahydro-pyran-2-carboxylic acid 
• 216769-45-8 (4R,5S,2'R,6'R)-2,2-dimethyl-5-(6'-hydroxymethylpyran-2'-yl)-4-phenyl-[1,3]dioxolane 
• 216769-50-5 (2R,6R,4'S,5'R)-6-(2',2'-dimethyl-5'-phenyl-[1,3]dioxolan-4'-yl)-pyran-2-carbaldehyde 
• 216769-61-8 (R)-6-((4S,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-tetrahydro-pyran-2-ol 
• 5707-04-0 Phenylselenyl chloride 

Downstream Products

• 146236-73-9 (+)-goniodiol 
• 163630-06-6 (6R,4'S,5'R)-6-(2',2'-dimethyl-5'-phenyl-[1',3']dioxolan-4'-yl)-5,6-dihydropyran-2-one 

Relevant articles and documents

A highly enantioselective total synthesis of (+)-goniodiol

A high-yielding enantioselective total synthesis of the bioactive styryllactone (+)-goniodiol has been realised, starting from readily available (S)-glycidol. A key step is an oxygen-to-carbon rearrangement of a silyl enol ether linked via an anomeric cen

A total synthesis of (+)-Goniodiol using an anomeric oxygen-to-carbon rearrangement

A new route to (+)-Goniodiol 1, a potent and selective cytotoxin, is described, using a diastereoselective oxygen-to-carbon rearrangement of an anomerically linked silyl enol ether as the key step.