891491-99-9

Basic information

• Product Name: (6-(DiMethylaMino)naphthalen-2-yl)Methanol
• Synonyms: (6-(DiMethylaMino)naphthalen-2-yl)Methanol
• CAS NO: 891491-99-9
• Molecular Formula: C13H15NO
• Molecular Weight: 201.2643
• Mol File: 891491-99-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 387.9±22.0 °C(Predicted)
• Appearance: /
• Density: 1.147±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 14.30±0.10(Predicted)
• CAS DataBase Reference: (6-(DiMethylaMino)naphthalen-2-yl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (6-(DiMethylaMino)naphthalen-2-yl)Methanol(891491-99-9)
• EPA Substance Registry System: (6-(DiMethylaMino)naphthalen-2-yl)Methanol(891491-99-9)

Safety Data

• Hazardous Substances Data: 891491-99-9(Hazardous Substances Data)

Usage

General Description

(6-(Dimethylamino)naphthalen-2-yl)methanol is a chemical compound with the molecular formula C14H15NO. It is a derivative of naphthalene, a polycyclic aromatic hydrocarbon, and contains a dimethylamino group and a hydroxymethyl group. (6-(DiMethylaMino)naphthalen-2-yl)Methanol is often used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active molecules. It has also been used as a reagent in the production of fluorescent dyes and optical brighteners. Additionally, (6-(Dimethylamino)naphthalen-2-yl)methanol has potential applications in the development of new materials and as a chemical probe in biological studies.

Upstream product

• 15231-91-1 6-bromo-naphthalen-2-ol 
• 173471-71-1 6‐(dimethylamino)‐2-naphthaldehyde 
• 5043-03-8 6?bromo?N,N?dimethylnaphthalen?2?amine 
• 5043-05-0 6-(N,N-dimethylamino)-2-naphthoic acid 
• 5043-06-1 methyl 6-(dimethylamino)-2-naphthoate 

Downstream Products

• 173471-71-1 6‐(dimethylamino)‐2-naphthaldehyde 

Relevant articles and documents

Histone deacetylase fluorescence probe, and preparation method and applications thereof

The invention provides a histone deacetylase fluorescence probe, and a preparation method and applications thereof. The structure formula of the histone deacetylase fluorescence probe is disclosed inthe invention. In synthesis, 6-(dimethylamino)-2-naphthaldehyde with two-photon effect is selected as a dye, so that further nucleophilic reaction is realized after deacetylation reaction, and fluorescence signals are generated; aldehyde group carbon is modified into cyanogroup alcohol structures, hydroxyl is connected with HDACs responsive groups, and the histone deacetylase fluorescence probe isused for detecting and imaging of the activity of histone deacetylase in tissue. According to the histone deacetylase fluorescence probe, cyanogroup with excellent electron-withdrawing capability isintroduced, so that after response of HDACs with the histone deacetylase fluorescence probe, intramolecular cyclization reaction is carried out rapidly, activation of fluorescence signals is realized,detecting and imaging on histone deacetylase in living cells and tissue are realized, and excellent clinical application value is achieved.

Prodan-containing nucleotide and use thereof

A compound represented by formula (1): wherein R1 is a substituent represented by formula (2): wherein R2 is ═O or —NH2, with the proviso that when R2 is ═O, H is attached to the 1-position N of the pyrimidine ring, and the bond between the 1-position N and the 6-position C is a single bond; or a substituent represented by formula (3): wherein R3 is —OH, ═O, or —NH2, with the proviso that when R3 is —OH or —NH2, R4 is H; when R3 is ═O, R4 is —NH2; and when R3 is ═O, H is attached to the 1-position N of the purine ring, and the bond between the 1-position N and the 6-position C is a single bond.