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89164-79-4

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89164-79-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 89164-79-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,1,6 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 89164-79:
(7*8)+(6*9)+(5*1)+(4*6)+(3*4)+(2*7)+(1*9)=174
174 % 10 = 4
So 89164-79-4 is a valid CAS Registry Number.

89164-79-4Downstream Products

89164-79-4Relevant articles and documents

Intensely potent morpholinyl anthracyclines

Acton,Tong,Mosher,Wolgemuth

, p. 638 - 645 (2007/10/02)

3'-Deamino-3'-(3-cyano-4-morpholinyl)doxorubicin is a new analogue that is 100 to 1000 times more potent than doxorubicin against tumors in cell culture or in mice, that is active by intraperitoneal, intravenous, or oral dosing, and that does not produce chronic myocardial lesions in mice. This analogue was encountered in studies on the reductive alkylation of doxorubicin and daunorubicin with 2,2'-oxybis[acetaldehyde], which constructs a morpholino ring incorporating the amino N. The morpholinyl nitrile byproducts are separated by virtue of their nonbasicity from the expected morpholino derivatives. The 13-dihydro and 5-imino derivatives are also described in this important new class of anthracyclines.

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