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3-PIPERAZIN-2-YL-PROPIONIC ACID, commonly referred to as PZP, is a chemical compound characterized by the molecular formula C8H16N2O2. It is a derivative of piperazine and structurally similar to the neurotransmitter gamma-aminobutyric acid (GABA). PZP has garnered attention for its potential pharmacological properties, which include its roles as an antipsychotic and anxiolytic agent. Its potential applications in treating conditions such as schizophrenia and bipolar disorder have been the subject of research. Furthermore, PZP's antioxidant and neuroprotective effects have positioned it as a compound of interest in neurology and the study of neurodegenerative diseases.

891782-61-9

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891782-61-9 Usage

Uses

Used in Pharmaceutical Industry:
3-PIPERAZIN-2-YL-PROPIONIC ACID is used as a potential therapeutic agent for the treatment of psychiatric disorders such as schizophrenia and bipolar disorder. Its structural similarity to GABA and its pharmacological properties suggest that it may help in managing the symptoms of these conditions by modulating neurotransmission.
Used in Neurological Research:
3-PIPERAZIN-2-YL-PROPIONIC ACID is utilized as a subject of study in the field of neurology, particularly for its antioxidant and neuroprotective effects. These properties make PZP a candidate for research into the prevention and treatment of neurodegenerative diseases, where oxidative stress and neuronal damage are significant factors.
Used in Drug Development:
3-PIPERAZIN-2-YL-PROPIONIC ACID is employed in the development of new drugs targeting the GABAergic system. Its potential as an anxiolytic and antipsychotic agent, along with its effects on neurotransmission, positions PZP as a valuable compound in the search for novel treatments for various neurological and psychiatric conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 891782-61-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,1,7,8 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 891782-61:
(8*8)+(7*9)+(6*1)+(5*7)+(4*8)+(3*2)+(2*6)+(1*1)=219
219 % 10 = 9
So 891782-61-9 is a valid CAS Registry Number.

891782-61-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-piperazin-2-ylpropanoic acid

1.2 Other means of identification

Product number -
Other names 2-Piperazinepropanoicacid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:891782-61-9 SDS

891782-61-9Relevant academic research and scientific papers

Dual antagonists of platelet activating factor and histamine. Part 3. Synthesis, biological activity and conformational implications of substituted N-acyl-bis-arylcycloheptapiperazines

Piwinski, John J.,Wong, Jesse K.,Green, Michael J.,Kaminski, James J.,Colizzo, Frank,Albanese, Margaret M.,Ganguly, Ashit K.,Billah, M. Motasim,Anthes, John C.,West Jr., Robert E.

, p. 3469 - 3474 (1998)

A series of N-acyl-4-(5,6-dihydro-11-H-benzo[5,6]cyclohepta[1,2- b]pyridin-11-ylidene)piperazines is described that are dual antagonists of PAF and histamine. The structural requirements for activity in this series parallel those of their previously reported piperidinylidene counterparts. Whereas their global minimum energy conformations are different for both series of compounds, computer assisted molecular modeling suggests that a common bioactive conformation is possible.

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