891832-10-3Relevant academic research and scientific papers
Novel alkoxybenzamide inhibitors of poly(ADP-ribose) polymerase
Menear, Keith A.,Adcock, Claire,Alonso, Francisco Cuenca,Blackburn, Kristel,Copsey, Louise,Drzewiecki, Jan,Fundo, Alexandra,Le Gall, Armelle,Gomez, Sylvie,Javaid, Hashim,Lence, Carlos Fenandez,Martin, Niall M.B.,Mydlowski, Chris,Smith, Graeme C.M.
scheme or table, p. 3942 - 3945 (2009/05/07)
We have previously described poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors based on a substituted benzyl-phthalazinone scaffold. As an alternative chemical template, a novel series of alkoxybenzamides were developed with restricted conformation throug
PARP inhibitors
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Page/Page column 23-24, (2008/06/13)
A compound of the formula (I): and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, wherein: R2, R3, R4 and R5 are independently selected from the group consisting of H, C1-7 /su
