891847-01-1Relevant academic research and scientific papers
Palladium(II)-catalyzed asymmetric synthesis of (Z)-α-alkylidene- γ-butyrolactams from (Z)-N-allylic 2-alkynamides. Total synthesis of (-)-isocynometrine
Xu, Wei,Kong, Aidi,Lu, Xiyan
, p. 3854 - 3858 (2006)
Pd(OAc)2 combined with nitrogen-containing ligands catalyzed the cyclization of (Z)-N-allylic 2-alkynamides in acetic acid to afford the α-(Z)-acetoxyalkylidene-γ-butyrolactams in high yield and high stereoselectivity. When chiral nitrogen-cont
