891862-22-9Relevant academic research and scientific papers
A short enantioselective pathway for the synthesis of the anti-influenza neuramidase inhibitor oseltamivir from 1,3-butadiene and acrylic acid
Yeung, Ying-Yeung,Hong, Sungwoo,Corey
, p. 6310 - 6311 (2006)
A short synthetic pathway has been developed for the synthesis of oseltamivir (1) or the enantiomer (ent-1). The intermediates and conditions for this process are summarized in Scheme 1. The synthesis provides a number of advantages: (1) use of inexpensiv
