89197-60-4 Usage
Description
Chroman-3-carbonitrile, also known as 3-Cyanochroman, is a heterocyclic chemical compound with the molecular formula C10H7NO. It features a nitrile group and is widely recognized for its unique chemical structure and properties, making it a valuable intermediate in pharmaceutical synthesis and a subject of interest for its potential pharmacological effects, such as antioxidant and anti-inflammatory activities.
Uses
Used in Pharmaceutical Industry:
Chroman-3-carbonitrile serves as a crucial intermediate in the synthesis of a variety of drugs. Its unique structure allows for the development of new medicinal compounds with specific therapeutic targets.
Used in Organic Synthesis:
Due to its reactive nitrile group and heterocyclic nature, chroMan-3-carbonitrile is utilized in organic synthesis for creating diverse chemical entities, contributing to the advancement of chemical research and the discovery of new materials.
Used in Drug Development:
chroMan-3-carbonitrile's potential pharmacological properties, including antioxidant and anti-inflammatory effects, position chroMan-3-carbonitrile as a candidate for drug development. It may be further studied and modified to create new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 89197-60-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,1,9 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 89197-60:
(7*8)+(6*9)+(5*1)+(4*9)+(3*7)+(2*6)+(1*0)=184
184 % 10 = 4
So 89197-60-4 is a valid CAS Registry Number.
89197-60-4Relevant articles and documents
α-Adrenoreceptor Reagents. 2. Effects of Modification of the 1,4-Benzodioxan Ring System on α-Adrenoreceptor Activity
Chapleo, Christopher B.,Myers, Peter L.,Butler, Richard C. M.,Davis, John A.,Doxey, John C.,et al.
, p. 570 - 576 (2007/10/02)
Modification of the 1,4-benzodioxan ring present in RX 781094 (1) has not previously been considered.This paper describes a number of analogues of this ring system, including compounds in which one of the oxygen atoms has been replaced by a methylene group and also those in which the ring size has been changed to give, for example, furan and thiophene derivatives.The dihydroxybenzofuranylimidazoline compound 7 is the only analogue possesing presynaptic antagonist potency and selectivity comparable to that of 1.In view of this result, a number of derivatives was prepared to determine the structure-activity relationships within this series.Many derivatives, as well as the parent compound 7, were found to possess presynaptic α2-adrenoreceptor antagonist and postsynaptic α1-adrenoreceptor partial agonist properties.Two of the selective presynaptic antagonists,13 and 14, possess greater potency and selectivity than that possessed by 1.The 5-chloro derivative 25 is twice as potent as 1 after oral administration but only about half as potent when given intravenously.
