89205-07-2 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
5-(4-Methoxyphenyl)-1,3-oxazole-4-carboxylic acid is used as a chemical intermediate for the synthesis of bioactive molecules, leveraging its structural features to contribute to the development of new drugs. Its oxazole ring and methoxyphenyl group may offer unique binding properties or pharmacological activities that can be harnessed in medicinal chemistry.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-(4-Methoxyphenyl)-1,3-oxazole-4-carboxylic acid is used as a building block for the design of new drugs. Its incorporation into drug candidates may enhance their pharmacokinetic and pharmacodynamic profiles, potentially leading to improved therapeutic agents.
Used in Chemical Synthesis:
5-(4-Methoxyphenyl)-1,3-oxazole-4-carboxylic acid is utilized as a reagent in various chemical synthesis processes. Its carboxylic acid functionality allows for a range of chemical reactions, making it a versatile component in the creation of complex organic molecules.
Used in Biochemical Studies:
5-(4-METHOXYPHENYL)-1,3-OXAZOLE-4-CARBOXYLIC ACID may also be employed in biochemical studies to probe the interactions between biological macromolecules and small molecules. Its structural elements could be key in understanding binding affinities and selectivity in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 89205-07-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,2,0 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 89205-07:
(7*8)+(6*9)+(5*2)+(4*0)+(3*5)+(2*0)+(1*7)=142
142 % 10 = 2
So 89205-07-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NO4/c1-15-8-4-2-7(3-5-8)10-9(11(13)14)12-6-16-10/h2-6H,1H3,(H,13,14)
89205-07-2Relevant academic research and scientific papers
5-Aryl-4-carboxamide-1,3-oxazoles: Potent and selective GSK-3 inhibitors
Gentile, Gabriella,Merlo, Giancarlo,Pozzan, Alfonso,Bernasconi, Giovanni,Bax, Benjamin,Bamborough, Paul,Bridges, Angela,Carter, Paul,Neu, Margarete,Yao, Gang,Brough, Caroline,Cutler, Geoffrey,Coffin, Aaron,Belyanskaya, Svetlana
scheme or table, p. 1989 - 1994 (2012/04/17)
5-Aryl-4-carboxamide-1,3-oxazoles are a novel, potent and selective series of GSK-3 inhibitors. The optimization of the series to yield compounds with cell activity and brain permeability is described.
Syntheses of 5-substituted oxazole-4-carboxylic acid derivatives with inhibitory activity on blood platelet aggregation
Ozaki,Maeda,Iwasaki,Matsumoto,Odawara,Sasaki,Morita
, p. 4417 - 4424 (2007/10/02)
Methyl 5-substituted oxazole-4-carboxylates were synthesized by the reaction of methyl α-isocyanoacetate with acylating reagents in the presence of bases. The oxazole methyl esters were converted into the carboxylic acids and the carboxamides. Then, N-alk
