892145-89-0

Upstream product

• 50-00-0 formaldehyd 
• 90-15-3 α-naphthol 
• 62-53-3 aniline 

Relevant academic research and scientific papers

An efficient green synthesis and antibacterial activity of 1,3-benzoxazine and 1,3-naphthoxazine using NaCl.SiO2 as solid catalyst in neat condition

A series of 1,3-oxazine derivatives were synthesized by a one-pot three-component (ie, phenol, formaldehyde, amine) method where SiO2 bonded with NaCl was used as a reusable, more efficient, easily prepared, and available solid catalyst. The reactions were also carried out at room temperature for greener approach. in vitro studies for the synthesized compounds were also done against two gram-positive (Bacillus subtilis and Staphylococcus aureus) and two gram-negative bacteria (Escherichia coli and Klebsiella pneumonia) to check for their applicability as an antibacterial agent where some of the synthesized compounds gives the best antibacterial activity against selected bacterial strains. Streptomycin was used as a standard control for all the microbial test.

Nano-Fe3O4?walnut shell/Cu(ii) as a highly effective environmentally friendly catalyst for the one-potpseudothree-component synthesis of 1,3-oxazine derivatives under solvent-free conditions

Fe3O4?walnut shell/Cu(ii) as an eco-friendly bio-based magnetic nano-catalyst was prepared by adding CuCl2to Fe3O4?walnut shell in alkaline medium. A series of 2-aryl/alkyl-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines were synthesized by the one-potpseudothree-component reaction of β-naphthol, formaldehyde and various amines using nano-Fe3O4?walnut shell/Cu(ii) at 60 °C under solvent-free conditions. The catalyst was removed from the reaction mixture by an external magnet and was reusable several times without any considerable loss of its activity. This protocol has several advantages such as excellent yields, short reaction times, clean and convenient procedure, easy work-up and use of an eco-friendly catalyst.

Etching resist underlayer film monomer, composition and pattern forming method

The invention belongs to the field of photoetching, and particularly relates to an etching resist underlayer film monomer, a composition and a pattern forming method. The etching resist underlayer film composition contains the etching resist underlayer film monomer represented by formula (1), a polymer and a solvent, wherein Ar1 represents an aryl group having 6 to 30 carbon atoms, and R1 represents an alkyl group having 1 to 6 carbon atoms or an aryl group having 6 to 30 carbon atoms. The etching resist underlayer film composition has excellent etching etching resistance, gap filling characteristics and planarization characteristics.

Novel and efficient microwave-assisted three component reaction for the synthesis of oxazine derivatives

Oxazine derivatives can be prepared with yield upto 98% within a few minutes by an efficient and novel one pot microwave-assisted three-component reaction from 1-naphthol, various anilines and formalin using montmorillonite as the catalyst. The procedure is very simple, efficient and environmentally friendly as it does not use any toxic auxiliary or solvent. The key advantages of this process are high yields, shorter reaction times, and easy work-up and non-chromatographic method has been used for the purification of products.

An efficient and green method for the synthesis of [1,3]oxazine derivatives catalyzed by thiamine hydrochloride (VB1) in water

An efficient and convenient synthesis of 1,3-oxazine derivatives has been achieved by the one-pot, multicomponent condensation of α- or β-naphthol, an aniline and formaldehyde using thiamine hydrochloride (VB1) as a versatile biodegradable and reusable catalyst in water as a universal solvent.

Polyethylene glycol (PEG) mediated expeditious synthetic route to 1,3-oxazine derivatives

Various 1,3-oxazine derivatives were synthesized in high yields, within shorter reaction times using PEG-400 as a safer medium/mediator. This synthetic route is exceedingly easy and avoids the use of acid/base catalysts.

An efficient synthesis of 3, 4-dihydro-3-substituted-2H-naphtho[2, 1-e][1, 3]oxazine derivatives catalyzed by zirconyl(IV) chloride and evaluation of its biological activities

An efficient and novel one-pot synthesis of new 3,4-dihydro-3-substituted- 2H-naphtho[2, 1-e][1, 3]oxazine derivatives from 1-naphthol, various anilines and formalin at room temperature grinding is presented. The six-membered N,O-heterocyclic skeleton was

An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives

A series of 3,4-dihydro-2H-benzo[e]-, 2,3-dihydro-1H-naphtho[1,2-e]-, 3,4-dihydro-2H-naphtho[2,1-e][1,3]oxazine and 1,2-bis(3,4-dihydrobenzo[e][1,3]oxazin-3(4H)-yl)ethane derivatives was obtained through an eco-friendly Mannich type condensation-cyclization reaction of phenols or naphthols with formaldehyde and primary amines in water at ambient temperature. Preliminary in vitro antimicrobial activity of the synthesized compounds was assessed against six pathogenic fungi, two Gram-negative and two Gram-positive bacteria. Some of the screened compounds have shown significant in vitro antimicrobial effect. Cytotoxic activities of the lead compounds (2m, 2n, 3c and 3d) against mouse fibroblast cell line (L929) were determined by MTT method. The assay results revealed that these molecules offered remarkable viability (>90%) of L929 cells at concentration of 25?μg/mL.

One-pot three-component synthesis of dihydrobenzo- and naphtho[e]-1,3- oxazines in water

(Chemical Equation Presented) A simple, green and efficient method has been developed for the synthesis of biologically and materially important dihydrobenzo/naphtho[e]-1,3-oxazines in good to excellent yields through a Mannich-type condensation cyclizati