89228-66-0Relevant academic research and scientific papers
TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY
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Page/Page column 214, (2008/06/13)
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Isomerization of 4-aminobenzofurans to 4-hydroxyindoles
Chilin,Rodighiero,Guiotto
, p. 309 - 312 (2007/10/03)
4-Amino-2-methylbenzofurans are quantitatively converted to 4-hydroxy- 2-methylindoles in acidic medium. The rearrangement mechanism involves the ring opening of the furan ring to produce an intermediate carbocation, which undergoes ring clo- sure to the
