89229-67-4Relevant academic research and scientific papers
Total synthesis of amaminol A: Establishment of the absolute stereochemistry
Kumpulainen, Esa T. T.,Koskinen, Ari M. P.,Rissanen, Kari
, p. 5043 - 5045 (2007)
The first synthetic route to amaminol A with use of an organocatalytic intramolecular Diels-Alder reaction is reported. The absolute stereochemistry is proven with a crystallographic image of a cyclic carbamate of amaminol A.
Asymmetric synthesis of 3,3,5,5-tetrasubstituted 1,2-dioxolanes: Total synthesis of epiplakinic acid F
Tian, Xiang-Yin,Han, Jian-Wei,Zhao, Qiong,Wong, Henry N. C.
, p. 3686 - 3700 (2014/06/09)
The first enantioselective total synthesis of epiplakinic acid F (1) was achieved through a pivotal step involving a radical-mediated asymmetric peroxidation of vinylcyclopropanes with molecular oxygen to construct highly substituted 1,2-dioxolanes. Subsequent conversions of the chiral 1,2-dioxolanes led to total synthesis of epiplakinic acid F (1) and the confirmation of its absolute configuration. The enantiomer of epiplakinic acid F methyl ester (2) was also prepared. This journal is the Partner Organisations 2014.
SYNTHESIS OF RACEMIC FECAPENTAENE-12, A POTENT MUTAGEN FROM HUMAN FECES, AND ITS REGIOISOMER
Gunatilaka, A. A. Leslie,Hirai, Nobuhiro,Kingston, David G. I.
, p. 5457 - 5460 (2007/10/02)
Racemic fecapentaene-12 and its regioisomer 2-(1,3,5,7,9-dodecapentaenyloxy)-1,3-propanediol (2) have been synthesized.The latter compound is comparably mutagenic to 1.
