89232-83-7 Usage
Description
Ursodeoxycholate-3-sulfate is a bile acid derivative that possesses anti-inflammatory and immunomodulatory properties. It is a major component of the natural bile acid pool, synthesized in the liver from cholesterol. Its primary function is to aid in the digestion and absorption of fats and fat-soluble vitamins in the small intestine.
Used in Pharmaceutical Industry:
Ursodeoxycholate-3-sulfate is used as a therapeutic agent for the treatment of liver diseases, such as cholestatic liver diseases and primary biliary cirrhosis. It helps alleviate symptoms and improve liver function due to its beneficial effects on bile flow and liver cell health.
Used in Gastroenterology:
Ursodeoxycholate-3-sulfate is used as a management tool for inflammatory bowel disease. Its anti-inflammatory properties help reduce inflammation in the gastrointestinal tract, providing relief and promoting gut health.
Used in Gut Microbiota Modulation:
Ursodeoxycholate-3-sulfate is used as a modulator of gut microbiota. It has been investigated for its potential role in influencing the composition and function of gut bacteria, which can contribute to overall gut health and immune system regulation.
Check Digit Verification of cas no
The CAS Registry Mumber 89232-83-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,2,3 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 89232-83:
(7*8)+(6*9)+(5*2)+(4*3)+(3*2)+(2*8)+(1*3)=157
157 % 10 = 7
So 89232-83-7 is a valid CAS Registry Number.
InChI:InChI=1/C24H40O10S2.3Na/c1-14(4-7-21(25)26)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(33-35(27,28)29)12-15(23)13-20(22)34-36(30,31)32;;;/h14-20,22H,4-13H2,1-3H3,(H,25,26)(H,27,28,29)(H,30,31,32);;;/q;3*+1/p-3/t14-,15+,16-,17-,18?,19?,20+,22?,23+,24-;;;/m1.../s1
89232-83-7Relevant articles and documents
Process for the preparation of ursodeoxycholic acid disodium 3,7-disulfate
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Page/Page column 5-6, (2010/09/05)
Process for preparing the disodium salt of ursodeoxycholic acid 3,7-disulfate comprising the following steps: a) reaction of ursodeoxycholic acid with a complex of trimethylamine-sulphuric anhydride, to obtain the ursodeoxycholic acid 3,7-disulfate di-trimethylammonium reaction intermediate; b) treatment of the di-trimethylammonium salt of ursodeoxycholic acid 3,7-disulfate with organic or inorganic sodium bases to obtain the tri-sodium salt of ursodeoxycholic acid 3,7-disulfate; c) treatment with an inorganic acid in presence of isopropanol up to a pH comprised in the range between 3.0 and 4.5, to obtain the disodium salt of ursodeoxycholic acid 3,7-disulfate in solution; d) removal of the salts present and obtaining the disodium salt ofursodeoxycholic acid 3,7-disulfate.
