892493-69-5

Basic information

• Product Name: (S)-1-Benzyl-2-iodoMethyl-pyrrolidine
• Synonyms: (S)-1-Benzyl-2-iodoMethyl-pyrrolidine;(2S)-1-benzyl-2-(iodomethyl)pyrrolidine
• CAS NO: 892493-69-5
• Molecular Formula: C12H16IN
• Molecular Weight: 301.16661
• Mol File: 892493-69-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-1-Benzyl-2-iodoMethyl-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-Benzyl-2-iodoMethyl-pyrrolidine(892493-69-5)
• EPA Substance Registry System: (S)-1-Benzyl-2-iodoMethyl-pyrrolidine(892493-69-5)

Safety Data

• Hazardous Substances Data: 892493-69-5(Hazardous Substances Data)

Upstream product

• 53912-80-4 (S)-N-benzylprolinol 

Relevant articles and documents

Copper(I) mediated cross-coupling of amino acid derived organozinc reagents with acid chlorides

This paper describes the development of a straightforward experimental protocol for copper-mediated cross-coupling of amino acid derived β-amido-alkylzinc iodides 1 and 3 with a range of acid chlorides. The present method uses CuCN·2LiCl as the copper source and for organozinc reagent 1 the methodology appears to be limited to reaction with more stable acid chlorides, providing the desired products in moderate yields. When applied to organozinc reagent 3, however, the protocol is more general and provides the products in good yields in all but one of the cases tested. The Royal Society of Chemistry 2006.