892495-05-5

Basic information

• Product Name: Piperazine, 1-[2-(acetyloxy)benzoyl]-4-[(trimethylpyrazinyl)methyl]-
• Synonyms: 2-(4-acetylsalicyloyl-1-piperazinomethyl)-3,5,6-trimethylpyrazine;Piperazine,1-[2-(acetyloxy)benzoyl]-4-[(trimethylpyrazinyl)methyl]
• CAS NO: 892495-05-5
• Molecular Formula: C21H26N4O3
• Molecular Weight: 382.462
• Mol File: 892495-05-5.mol

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-[2-(acetyloxy)benzoyl]-4-[(trimethylpyrazinyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-[2-(acetyloxy)benzoyl]-4-[(trimethylpyrazinyl)methyl]-(892495-05-5)
• EPA Substance Registry System: Piperazine, 1-[2-(acetyloxy)benzoyl]-4-[(trimethylpyrazinyl)methyl]-(892495-05-5)

Safety Data

• Hazardous Substances Data: 892495-05-5(Hazardous Substances Data)

Upstream product

• 892396-47-3 2,3,5-trimethyl-6-(piperazin-1-ylmethyl)pyrazine 
• 5538-51-2 O-acetylsalicyloyl chloride 

Downstream Products

• 892495-43-1 2-(4-salicyloyl-1-piperazinomethyl)-3,5,6-trimethylpyrazine 

Relevant articles and documents

Ligustrazine derivatives. Part 3: Design, synthesis and evaluation of novel acylpiperazinyl derivatives as potential cerebrocardiac vascular agents

A series of novel acylpiperazinyl Ligustrazine derivatives was designed, synthesized, and their protective effects on damaged ECV-304 cells and antiplatelet aggregation activities were evaluated. The results showed that compound E33 displayed most potential protective effects on the ECV-304 cells damaged by hydrogen peroxide, and compound E1 was found to be the most active antiplatelet aggregation agent. Structure-activity relationships were briefly discussed.