892496-01-4Relevant academic research and scientific papers
Synthesis of N(3),N′(3)-polymethylene-bis-hydantoins and their macrocyclic derivatives
Dieltiens, Nicolai,Claeys, Diederica D.,Stevens, Christian V.
, p. 3863 - 3868 (2007/10/03)
An efficient and straightforward two-step approach toward N(3),N′(3)-polymethylene-bis-hydantoins was developed. As a first step, a pyroglutamate is reacted with a diisocyanate to produce a bis-carbamoyllactam. The second step is a double-ring transformat
