892502-26-0

Basic information

• Product Name: ETHYL 4-(4-METHYL-1,4-DIAZEPAN-1-YL)BENZOATE 97
• Synonyms: ETHYL 4-(4-METHYLPERHYDRO-1,4-DIAZEPIN-1-YL)BENZOATE;ETHYL 4-(4-METHYL-1,4-DIAZEPAN-1-YL)BENZOATE;ETHYL 4-(4-METHYL-1,4-DIAZEPAN-1-YL)BENZOATE 97;Ethyl 4-(4-methyl-1,4-diazepan-1-yl)benzoate 97%
• CAS NO: 892502-26-0
• Molecular Formula: C15H22N2O2
• Molecular Weight: 262.34738
• Mol File: 892502-26-0.mol

Chemical Properties

• Boiling Point: 391.5°C at 760 mmHg
• Flash Point: 190.5°C
• Appearance: /
• Density: 1.071g/cm³
• Vapor Pressure: 2.46E-06mmHg at 25°C
• Refractive Index: 1.53
• CAS DataBase Reference: ETHYL 4-(4-METHYL-1,4-DIAZEPAN-1-YL)BENZOATE 97(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-(4-METHYL-1,4-DIAZEPAN-1-YL)BENZOATE 97(892502-26-0)
• EPA Substance Registry System: ETHYL 4-(4-METHYL-1,4-DIAZEPAN-1-YL)BENZOATE 97(892502-26-0)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 892502-26-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H22N2O2/c1-3-19-15(18)13-5-7-14(8-6-13)17-10-4-9-16(2)11-12-17/h5-8H,3-4,9-12H2,1-2H3

Upstream product

• 4318-37-0 1-Methylhomopiperazine 
• 451-46-7 4-fluorobenzoic acid ethyl ester 

Relevant articles and documents

Discovery of Substituted 1H-Pyrazolo[3,4-b]pyridine Derivatives as Potent and Selective FGFR Kinase Inhibitors

Fibroblast growth factor receptors (FGFRs) are important targets for cancer therapy. Herein, we describe the design, synthesis, and biological evaluation of a novel series of 1H-pyrazolo[3,4-b]pyridine derivatives as potent and selective FGFR kinase inhibitors. On the basis of its excellent in vitro potency and favorable pharmacokinetic properties, compound 7n was selected for in vivo evaluation and showed significant antitumor activity in a FGFR1-driven H1581 xenograft model. These results indicated that 7n would be a promising candidate for further drug development.

Pyrazolo [3,4 - the b] pyridine and [...] composition preparation method and use of (by machine translation)

The present invention provides a pyrazolo [3,4 - the b] pyridine and [...] compound of preparation and use, in particular, the present invention provides a following formula (I) compounds are shown, wherein the definition of each group as described in the specification. The compounds of the invention has excellent tyrosine kinase inhibiting activity, so can be used for preparing a series of treating diseases associated with the tyrosine kinase activity of the drug. (by machine translation)