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HETEROCYCLIC SUBSTITUTED AMINO ACIDS VIA α,β-DEHYDROAMINO ACID DERIVATIVES. STUDIES ON AMINO ACIDS III
Herdeis, Claus,Nagel, Urlich
, p. 2163 - 2167 (2007/10/02)
Condensation of lactam acetals 2a,b with isocyanacetic esters give 3a,b.The Z-configuration of 3a (R1=CH3, R2=C2H5) was determined by X-ray diffraction.Reaction with ethyl N-(ethoxycarbonyl)glycinate gives the protected α,β-dehydroam
