892860-31-0

Basic information

• Product Name: C₅₆H₇₃N₃O₁₇
• Synonyms: C₅₆H₇₃N₃O₁₇
• CAS NO: 892860-31-0
• Molecular Weight: 1060.21
• Mol File: 892860-31-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₆H₇₃N₃O₁₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₆H₇₃N₃O₁₇(892860-31-0)
• EPA Substance Registry System: C₅₆H₇₃N₃O₁₇(892860-31-0)

Safety Data

• Hazardous Substances Data: 892860-31-0(Hazardous Substances Data)

Upstream product

• 860476-69-3 C₄₈H₆₄N₂O₁₇ 
• 4732-11-0 O-(2-phenylethyl)hydroxylamine 

Relevant articles and documents

A new type of ketolide bearing an N-aryl-alkyl acetamide moiety at the C-9 iminoether: Synthesis and structure-activity relationships (2)

A new type of ketolide bearing an N-aryl-alkyl acetamide moiety at the C-9 iminoether and its analogues were prepared, and their antibacterial activities and pharmacokinetic properties were evaluated. We found that the introduction of an (R)-alkyl group between the amide and iminoether groups could improve the pharmacokinetic properties while maintaining the activity against erythromycin-resistant Streptococcus pneumoniae. Among the ketolides prepared with the (R)-alkyl group, compound 5p with an N-(3-quinoxalin-6-yl-propyl)-propionamide moiety was found to have in vivo efficacy comparable to CAM with potent in vitro antibacterial activities against the key respiratory pathogens including Haemophilus influenzae and erythromycin-resistant S. pneumoniae.