89290-99-3Relevant academic research and scientific papers
1-Substituted Imidazoles as Useful Catalysts for Acylation of Alcohols
Kamijo, Tetsuhide,Yamamoto, Ryoji,Harada, Hiromu,Iizuka, Kinji
, p. 3724 - 3727 (2007/10/02)
Acylation of alcohols with acid anhydrides or acid halides could be considerably accelerated by adding 1-substituted imidazoles as catalysts.The acylation with acid halides required the addition of triethylamine to capture the resulting acid. 1-Isopropyl-5-methylimidazole and 1-(4-methoxybenzyl)-5-methylimidazole showed higher catalytic activities than 4-dimethylaminopyridine (DMAP) for acylation of primary and secondary alcohols. Keywords ---- 1-substituted imidazole; acylating catalyst; 1-isopropylimidazole; 1-isopropyl-5-methylimidazole; 1-(4-methoxybenzyl)-5-methylimidazole; 4-dimethylaminopyridine
