89328-43-8Relevant articles and documents
261. Construction of Large Carbocyclic Rings by Ireland-Claisen Rearrangement of O-Silylated Lactone Enolates: Synthesis of (+/-)-Muscone
Brunner, Rudolf K.,Broschberg, Hans-Juerg
, p. 2608 - 2614 (2007/10/02)
(+/-)-Muscone (5) has been synthesized from methyl 13-(chloroformyl)tridecanoate (6) in nine steps in an averall yield of 24 percent.The key steps involve an efficient transformation of the readily accessible 14-hydroxy-15-methyl-15-hexadecenoic acid (9)