89328-79-0Relevant academic research and scientific papers
A Novel Pentaannulation Sequence. Facile Access to Key Intermediates for the Synthesis of ExaltoneR and Muscone
Fehr, Charles
, p. 2519 - 2524 (2007/10/02)
Treatment of the sulfonyl ketones 1 a and 1 b with potassium t-butoxide in toluene or with potassium hydroxyde in toluene/dimethyl sulfoxide affords in high yield the bicyclic dienes 3 a and 3 b, importantbprecursors for exaltoneR and (+/-)-muscone.An Application of this novell pentaannulation sequence is demonstrated for the solfonyl ketones 6, 10, and 14.An intermolecular variant is exemplified by the synthesis of diene 22.
