893429-36-2

Upstream product

• 112-20-9 n-Nonylamin 
• 952481-10-6 acetic acid 3-(2-bromo-ethoxy)-4-methoxy-benzyl ester 
• 893429-32-8 (3-(2-bromoethoxy)-4-methoxyphenyl)methanol 
• 219685-46-8 3-(2-bromoethoxy)-4-methoxy benzaldehyde 
• 893429-34-0 3-[3-(2-bromo-ethoxy)-4-methoxy-phenyl]-2-methyl-propionic acid methyl ester 
• 850724-06-0 2-(nonylamino)pyridine 
• 621-59-0 isovanillin 
• 109-04-6 2-bromo-pyridine 

Relevant academic research and scientific papers

Synthesis and evaluation of 2-nonylaminopyridine derivatives as PPAR ligands

To find novel PPAR ligands, we prepared several 3-{3 or 4-[2-(nonylpyridin-2-ylamino)ethoxy]phenyl}-propanoic acid derivatives which were designed based on the structure of our previous PPARγ ligand 1. In PPAR binding affinity assays, compound 4, which ha

Identification of novel PPARα ligands by the structural modification of a PPARγ ligand

To develop novel PPARα ligands, we designed and synthesized several 3-{3-[2-(nonylpyridin-2-ylamino)ethoxy]phenyl}propanoic acid derivatives. Compound 10, the meta isomer of a PPARγ agonist 1, has been identified as a PPARα ligand. The introduction of methyl and ethyl groups at the C-2 position of the propanoic acid of 10 further improved the PPARα-binding potency.