89356-59-2

Upstream product

• 89356-56-9 2-amino-1-(4-benzyloxy-3-methoxyphenyl)propane hydrochloride 
• 89356-58-1 3-(3-Benzyloxy-4,5-dimethoxy-phenyl)-propionyl chloride 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 89356-57-0 3-(3-benzyloxy-4,5-dimethoxyphenyl)propionic acid 
• 89356-55-8 E-2-(4-benzyloxy-3-methoxyphenyl)-1-methyl-1-nitroethane 

Downstream Products

• 89356-61-6 trans-1-<2-(3-benzyloxy-4,5-dimethoxyphenyl)ethyl>-7-benzyloxy-6-methoxy-2,3-dimethyl-1,2,3,4-tetrahydroisoquinoline 
• 89356-61-6 cis-1-<2-(3-benzyloxy-4,5-dimethoxyphenyl)ethyl>-7-benzyloxy-6-methoxy-2,3-dimethyl-1,2,3,4-tetrahydroisoquinoline 
• 89356-66-1 trans-7-hydroxy-1-<2-(3-hydroxy-4,5-dimethoxyphenyl)ethyl>-6-methoxy-2,3-dimethyl-1,2,3,4-tetrahydroisoquinoline 
• 89356-66-1 cis-7-hydroxy-1-<2-(3-hydroxy-4,5-dimethoxyphenyl)ethyl>-6-methoxy-2,3-dimethyl-1,2,3,4-tetrahydroisoquinoline 
• 89356-60-5 1-<2-(3-benzyloxy-4,5-dimethoxyphenyl)ethyl>-7-benzyloxy-6-methoxy-2,3-dimethyl-3,4-dihydroisoquinolinium iodide 

Relevant academic research and scientific papers

Biosynthesis. Part 26. Synthetic Studies of Structural Modification of Late Biosynthetic Precursors for Colchicine

The latter part of the natural pathway to colchicine is known to involve conversion of phenethyltetrahydroisoquinoline (2) by phenol oxidation into a dienone (O-methylandrocymbine) (4), the dienone subsequently undergoing ring-expansion to generate the tr