89371-79-9

Basic information

• Product Name: tert-butyl (4S)-3-<(2R)-2-propionyl>-1-methyl-2-oxoimidazolidine-4-carboxylate
• Synonyms: tert-butyl (4S)-3-<(2R)-2-propionyl>-1-methyl-2-oxoimidazolidine-4-carboxylate
• CAS NO: 89371-79-9
• Molecular Weight: 523.629
• Mol File: 89371-79-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl (4S)-3-<(2R)-2-propionyl>-1-methyl-2-oxoimidazolidine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (4S)-3-<(2R)-2-propionyl>-1-methyl-2-oxoimidazolidine-4-carboxylate(89371-79-9)
• EPA Substance Registry System: tert-butyl (4S)-3-<(2R)-2-propionyl>-1-methyl-2-oxoimidazolidine-4-carboxylate(89371-79-9)

Safety Data

• Hazardous Substances Data: 89371-79-9(Hazardous Substances Data)

Upstream product

• 83080-02-8 benzyl (2S)-2-amino-4-phenylbutyrate 
• 195828-75-2 tert.-butyl (4S)-1-methyl-3-(2-bromopropionyl)-2-oxo-imidazolidine-4-carboxylate 
• 143996-80-9 tert-butyl (4S)-1-methyl-3-<(2S)-2-(4-toluenesulfonyloxy)propionyl>-2-oxoimidazolidine-4-carboxylate 

Downstream Products

• 118016-66-3 (4S)-3-<(2R)-2-propionyl>-1-methyl-2-oxoimidazolidine-4-carboxylic acid 

Relevant articles and documents

Studies on angiotensin converting enzyme inhibitors. VI. Synthesis and angiotensin converting enzyme inhibitory activities of the dicarboxylic acid derivative of imidapril and its diastereoisomers

All possible diastereoisomers of the dicarboxylic acid (10a), the biologically active form of imidapril (1), were synthesized, and their inhibitory activity against angiotensin converting enzyme (ACE) was examined. The in vitro ACE inhibitory activity of these compounds greatly depended on the configurations of the three asymmetric carbons in each molecule. The (S,S,S) isomer (10a) showed much more potent activity than the others.