893737-91-2Relevant academic research and scientific papers
Design, Synthesis and SAR Studies of Novel and Potent Dipeptidyl Peptidase 4 Inhibitors
Luo, Na,Fang, Xiaoyu,Su, Mingbo,Zhang, Xinwen,Li, Dan,Li, Honglin,Li, Shiliang,Zhao, Zhenjiang
, p. 115 - 120 (2021)
Dipeptidyl peptidase 4 (DPP-4) is a clinically validated target for the treatment of type 2 diabetes mellitus (T2DM). To discover novel and potent DPP-4 inhibitors, three series of compounds were designed and synthesized in this study based on our previou
IRE-1A INHIBITORS
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Page/Page column 100; 114, (2009/01/24)
Compounds which directly inhibit IRE-lα activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
