89378-72-3

Upstream product

• 69383-70-6 3-(1-pyrrolidinylmethyl)-phenol 
• 5332-06-9 4-bromobutanenitrile 

Downstream Products

• 149071-72-7 2-{2-[3-(3-Pyrrolidin-1-ylmethyl-phenoxy)-propyl]-1H-imidazol-4-yl}-ethanol 
• 149071-85-2 2-(2-{2-[3-(3-Pyrrolidin-1-ylmethyl-phenoxy)-propyl]-1H-imidazol-4-yl}-ethyl)-isoindole-1,3-dione 
• 149071-83-0 4-(2-Chloro-ethyl)-2-[3-(3-pyrrolidin-1-ylmethyl-phenoxy)-propyl]-1H-imidazole 

Relevant academic research and scientific papers

CHEMICAL COMPOUNDS

This invention relates to 5-oxypyrimidinone compounds having H. sub.2-antagonist activity. A particular compound of the invention is 2-3-(3-piperidinomethyl)phenoxy)propyl!-5-benzyloxypyrimidin-4-one.

Histamine H2 receptor antagonists. 1. Synthesis of N-cyano and N-carbamoyl amidine derivatives and their biological activities.

A large number of N-cyano amidine derivatives were prepared as potential histamine H2 receptor antagonists and evaluated for their inhibitory action on histamine-stimulated chronotropic response of isolated right atria from guinea pigs. Several selected c