89401-67-2

Usage

Uses

Used in Pharmaceutical Applications:
2-Pyridin-4-yl-thiazol-4-ylamine is used as a potential inhibitor of various enzymes and proteins, which makes it valuable in the development of new drugs and therapies for a range of medical conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-Pyridin-4-yl-thiazol-4-ylamine is utilized for chemical research and drug development, allowing scientists to explore its properties and potential interactions with biological targets.

Upstream product

• 692889-71-7 tert-butyl N-(2-pyridin-1,3-thiazol-4-yl)carbamate 
• 630409-36-8 N-(2-pyridin-4-yl-1,3-thiazol-4-yl)prop-2-enyloxycarboxamide 

Downstream Products

• 1240521-42-9 (S)-3-phenyl-N-(2-(pyridin-4-yl)thiazol-4-yl)-2-(thiazol-4-ylmethylamino)propanamide 
• 1240521-41-8 (S)-2-amino-3-phenyl-N-(2-(pyridin-4-yl)thiazol-4-yl)propanamide 
• 1240521-40-7 (S)-tert-butyl 1-oxo-3-phenyl-1-(2-(pyridin-4-yl)thiazol-4-ylamino)propan-2-ylcarbamate 
• 630411-31-3 3-nitro-4-{[(2-(pyridin-4-yl)(1,3-thiazol-4-yl))amino]methyl}phenol 

Relevant academic research and scientific papers

COMPOSITIONS USEFUL AS INHIBITORS OF ROCK AND OTHER PROTEIN KINASES

The present invention relates to substitute thiazole and thiophene derivatives useful as inhibitors of rock and other protein kinaeses. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders, including proliferative, cardiac and neurodegenerative diseases.

2-oxo-1,3,4-trihydroquinazolinyl derivatives and methods of use

Selected compounds are effective for treatment of diseases, such as cell proliferation or apoptosis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving stroke, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

2-(4'-Pyridinyl)-thiazole compounds and their use in increasing cardiac contractility

The pyridinyl-thiazole derivatives of the present invention exhibit good cardiotonic activity.