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89408-03-7

89408-03-7

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89408-03-7 Usage

Derivation

Derived from thiophene and thiazole

Usage in Pharmaceutical Industry

Acts as a ligand for metal ions: cobalt, copper, zinc

Biological Properties

Anti-inflammatory: Demonstrated in in vitro and in vivo studies
Antioxidant: Shown in various research settings
Anticancer: Exhibited potential against cancer cells
Antimicrobial: Effective against pathogenic bacteria and fungi

Potential for Drug Development

Promising candidate for new drug development

Medical Applications

Potential in various medical applications due to its diverse biological activities

Research Focus

Considered as a target for further research in drug development and medical applications

Check Digit Verification of cas no

The CAS Registry Mumber 89408-03-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,4,0 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 89408-03:
(7*8)+(6*9)+(5*4)+(4*0)+(3*8)+(2*0)+(1*3)=157
157 % 10 = 7
So 89408-03-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3S2/c1-7(8-3-2-5-13-8)11-12-9-10-4-6-14-9/h2-6H,1H3,(H,10,12)/b11-7-

89408-03-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(1-thiophen-2-ylethylideneamino)-1,3-thiazol-2-amine

1.2 Other means of identification

Product number -
Other names 2-acetylthiophene-2-thiazolylhydrazone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:89408-03-7 SDS

89408-03-7Downstream Products

89408-03-7Relevant articles and documents

Inhibiteurs mixtes des voies de la cyclooxygenase et des lipoxygenases: synthese et activite de derives hydrazoniques

Ghiglieri-Bertez, Chantal,Coquelet, Claude,Alazet, Alain,Bonne, Claude

, p. 147 - 152 (2007/10/02)

Dual inhibitors of the cyclooxygenase and lipoxygenase pathways: synthesis and activity of hydrazone derivatives.Non-steroidal anti-inflammatory drugs (NSAIDs) act by preventing prostaglandin production.In recent years, research on non-steroid dual inhibitors of prostaglandin and leukotriene biosyntheses has been developed.These compounds should represent a new class of anti-inflammatory drugs, with a wider spectrum of activity than classical NSAIDs.The present paper reports the synthesis of hydrazone derivatives.The effect of various substitutions is studied on platelet cyclooxygenase (i.e. prostaglandin synthesis) and on leukocyte 5-lipoxygenase (i.e. leukotriene synthesis).Among the 50 tested compounds, 2 hydrazone derivatives were selected for their significant dual inhibitory potency: 2-acetylthiophene-2-thiazolylhydrazone 5g, and N-phenyl benzimidrazone 6c.Keywords - non-steroidal anti-inflammatory drugs / hydrazones / dual inhibitor / cyclooxygenase / lipoxygenase

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