89430-05-7Relevant academic research and scientific papers
Organic catalysis of phospha-aldol condensation
Kolodyazhnaya,Kukhar,Kolodyazhnyi
experimental part, p. 2043 - 2051 (2009/04/13)
Phospha-aldol reaction of dialkylphosphites with carbonyl compounds is catalyzed by cinchonine alkaloids and thier modified derivatives to give optically active hydroxyphosphonates. The use of diastereomeric pairs of alkaloids allowed obtaining both optic
ASYMMERIC CATALYSIS IN CARBON-PHOSPHORUS BOND FORMATION
Wynberg, Hans,Smaardijk, Ab A.
, p. 5899 - 5900 (2007/10/02)
o-Nitrobenzaldehyde reacts smoothly with dialkylphosphonates in the presence of catalytic quantities of cinchona alkaloids (e.g.quinine) to produce the α-hydroxy phosphonate esters in excellent chemical yields, with excellent enantiomeric enrichment.
