894351-74-7

Upstream product

• 894351-73-6 {(1S,2S,5R)-2-[6-(tert-Butyl-diphenyl-silanyloxy)-hexyl]-5-hydroxy-cyclopentyl}-acetic acid methyl ester 
• 827325-81-5 4-[6-(tert-butyl-diphenyl-silanyloxy)-hexyl]-hexahydro-cyclopenta[b]furan-2-one 
• 827325-80-4 ((1S,2S)-2-[6-{(tert-butyldiphenylsilyl)oxy}hexyl]cyclopent-4-en-1-yl)acetic acid 
• 894351-71-4 (1R,4S)-4-[6-{(tert-butyldiphenylsilyl)oxy}hexyl]-2-cyclopentenyl acetate 
• 827325-79-1 ((1S,2S)-2-[6-{(tert-butyldiphenylsilyl)oxy}hexyl]cyclopent-4-en-1-yl)ethanal 
• 827325-91-7 (1R,4S)-4-[6-{(tert-butyldiphenylsilyl)oxy}hexyl]-2-cyclopenten-1-ol 
• 994-30-9 triethylsilyl chloride 
• 894351-72-5 (3aS,4S,6S,6aS)-4-[6-(tert-Butyl-diphenyl-silanyloxy)-hexyl]-6-iodo-hexahydro-cyclopenta[b]furan-2-one 
• 60410-16-4 (1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate 
• 827325-82-6 {(1S,2S,5R)-2-[6-(tert-Butyl-diphenyl-silanyloxy)-hexyl]-5-triethylsilanyloxy-cyclopentyl}-acetic acid methyl ester 

Downstream Products

• 827325-83-7 C₃₈H₆₂O₂Si₂ 

Relevant academic research and scientific papers

Synthesis of Δ2-OPC-8:0 and OPC-6:0

CuCN-catalyzed reaction of the (1R)-isomer of 4-cyclopentene-1,3-diol monoacetate with TBDPSO(CH2)6MgCl produced an SN2-type product regioselectively in high yield. Mitsunobu inversion of the product and subsequent Claisen

Synthesis of Δ2-OPC-8:0 and OPC-6:0

Δ2-OPC-8:0 (6), designed as a β-oxidation-insensitive analogue, was synthesized starting with 4-cyclopentene-1,3-diol monoacetate (5) in a stereocontrolled manner. The C(3)-C(8) moiety was first attached to the cyclopentene ring by using the Cu