89449-83-2Relevant academic research and scientific papers
Henry reaction and 1,4-addition of nitroalkanes to α,β- unsaturated carbonyl compounds under the influence of MS 4 A in DMSO
Oriyama, Takeshi,Aoyagi, Masaru,Iwanami, Katsuyuki
, p. 612 - 613 (2008/02/07)
In the presence of MS 4 A in DMSO (dimethyl sulfoxide), Henry reaction with various carbonyl compounds and nitroalkanes proceeded smoothly to give the corresponding β-nitroalcohol without a base catalyst. Moreover, 1,4-additon of nitroalkane to α,β-unsaturated ketones was also performed in DMSO. Copyright
Tandem Hass-Bender/Henry reaction for the synthesis of dimethylnitro alcohols from benzylic halides
Klein, Thomas A.,Schkeryantz, Jeffrey M.
, p. 4535 - 4538 (2007/10/03)
Dimethylnitro alcohols are constructed in a one-pot process from benzylic halides and 2-nitropropane. The use of tetrabutylammonium fluoride (TBAF) as the promoter is essential for this tandem Hass-Bender/Henry reaction to proceed.
Asymmetric synthesis of highly substituted β-nitro alcohols and enantiomerically enriched 4,4,5-trisubstituted oxazolidinones
Crich, David,Ranganathan, Krishnakumar,Rumthao, Sochanchingwung,Shirai, Michio
, p. 2034 - 2037 (2007/10/03)
It is demonstrated that α,α-disubstituted-α-nitroketones are reduced to the corresponding trisubstituted nitro alcohols in good to excellent yield and enantiomeric excess by borane-dimethyl sulfide in the presence of a chiral oxazaborolidine catalyst. Red
Nitroaldol (Henry) reaction catalyzed by amberlyst A-21 as a far superior heterogeneous catalyst
Ballini, Roberto,Bosica, Giovanna,Forconi, Paola
, p. 1677 - 1684 (2007/10/03)
β-Nitroalcohols can be efficiently obtained with the help of Amberlyst A-21, as heterogeneous basic catalyst, with or without solvent. This method is far superior to the heterogeneous catalysts previously reported for the nitroaldol (Henry) reaction, in f
